Leptobrachium hendricksoni is a species particularly known from Sumatra and Peninsular Malaysia. Bornean records exist in the literature, but the species is not commonly found and some literature records may also be misidentifications. More research is needed. 

The species occurs in swampy lowland forest. Males reach a snout-vent length (SVL) of 39–48 mm, females grow larger, up to 52–80 mm SVL. Leptobrachium frog species are relatively stout-bodied with long, thin legs and a big head.

The species is brown to gray above with darker dorsolateral spots; the coloration is optimised for camouflage in the leaf litter. A striking features is the red, orange or yellow iris of this species. Like other species in the genus, they are opportunistic predators. They feed on various invertebrates available on the ground layer. Due to the relatively broad head, they are able to engulf larger prey items, such as cockroaches or even possibly smaller frogs.

The tadpoles of Leptobrachium hendricksoni have been described long time ago but images are rare. Thanks to the courtesy of ©Nick Baker (Ecology Asia) we can present photos here as well as an adult from Peninsular Malaysia (courtesy ©Roy Kittrell) . As other species in the genus, the tadpoles of L. hendricksoni are large and heavily built. What sets them apart, however, from the tadpoles of for example L. abbotti is the unique pattern with black dots in L. hendricksoni. L. hendricksoni tadoples live in quiet sections of lowland streams.